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Invited Speaker: Dr. Mohammad Reza Raoufy

Invited Speaker: Dr. Mohammad Reza Raoufy

Invited Speaker: Dr. Mohammad Reza Raoufy

Associate Professor of Physiology

Department of Physiology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran



2008-2012       PhD in Physiology, Tarbiat Modares University, Tehran, Iran

2000-2008       Medical Doctor (MD), Shahid Beheshti University of Medical Sciences, Tehran, Iran




Non-invasive brain stimulation through olfactory pathway to reduce neurocognitive dysfunction

In nasal breathing, the airflow activates mechanosensitive olfactory sensory neurons (OSNs) of the nasal epithelium and entrains oscillatory neural activity in the olfactory bulb (OB). Besides processing odorant information, OSNs also respond to mechanical stimulation of airflow passage. Rhythmic OB activation by nasal breathing generates respiration-coupled oscillations propagating throughout the cortical and subcortical regions implicated in cognitive functions such as learning and memory. Interestingly, nasal breathing diversion to the oral root as well as OB inhibition or OSN ablation abolishes these respiration-entrained brain rhythms, which are subsequently associated with cognitive impairments. Based on our recent studies, it seems that stimulating olfactory pathway can improve neural homeostasis and notably reduce neurocognitive dysfunction.